Gene symbol | PLK1 | Synonyms | PLK, STPK13 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p12.2 | dbXrefs | |
Description | polo like kinase 1 |
GTO ID | GTC1370 |
Trial ID | NCT01262235 |
Disease | Adrenocortical Carcinoma | Neuroendocrine Tumor | Cancer |
Altered gene | PLK1 |
Therapeutic/Target gene | Target gene |
Therapy | siRNA |
Treatment | TKM-080301|PLK1 SNALP|TKM-PLK1 |
Phase | Phase1|Phase2 |
Recruitment status | Completed |
Title | A Phase 1/2 Dose Escalation Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of Intravenous TKM-080301 in Patients With Advanced Solid Tumors |
Year | 2010 |
Country | United States |
Company sponsor | Arbutus Biopharma Corporation |
Other ID(s) | TKM-PLK1-001 |
Vector information | |||
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Cohort 1 | |||||||||
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