Gene symbol | PMEL | Synonyms | D12S53E, HMB-45, HMB45, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV, gp100 | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12q13.2 | dbXrefs | |
Description | premelanosome protein |
GTO ID | GTC1368 |
Trial ID | NCT01211262 |
Disease | Malignant Adenoma |
Altered gene | gp100 |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | gp100 TCR-T cells |
Phase | Phase1 |
Recruitment status | Completed |
Title | A Phase 1, Open Label, Dose Finding Study to Assess the Safety and Tolerability of IMCgp100, a Monoclonal T Cell Receptor Anti-CD3 scFv Fusion Protein in Patients With Advanced Malignant Melanoma |
Year | 2010 |
Country | United States |
Company sponsor | Immunocore Ltd |
Other ID(s) | IMCgp100/01|2010-019290-15 |
Cohort 1 | |||||||||
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