Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1365
Trial ID NCT01195480
Disease Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
PhasePhase1|Phase2
Recruitment statusTerminated
TitleCD19-CAR Immunotherapy for Childhood Acute Lymphoblastic Leukemia (ALL)
Year2012
CountryUnited Kingdom
Company sponsorUniversity College, London
Other ID(s)UCL/09/0050|2007-007612-29
Vector information
Vectorretrovirus
ConstructscFv-CD3ζ
Additional featureEBV-specific

Clinical Result

Cohort 1
Administration route infusion
Dosage 2E8 cells/m^2
Pts 29
Age Child, Adult

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