Gene symbol | CCR5 | Synonyms | CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 | Type of gene | protein-coding | |
Chromosome | 3 | Map location | 3p21.31 | dbXrefs | Entrez:1234 MIM:601373 HGNC:HGNC:1606 Ensembl:ENSG00000160791 AllianceGenome:HGNC:1606 | |
Gene perturbation-related omics dataset | PertOrg | |||||
Description | C-C motif chemokine receptor 5 |
Gene symbol | RBM8A | Synonyms | BOV-1A, BOV-1B, BOV-1C, C1DELq21.1, DEL1q21.1, MDS014, RBM8, RBM8B, TAR, Y14, ZNRP, ZRNP1 | Type of gene | protein-coding | |
Chromosome | 1 | Map location | 1q21.1 | dbXrefs | Entrez:9939 MIM:605313 HGNC:HGNC:9905 Ensembl:ENSG00000265241 AllianceGenome:HGNC:9905 | |
Gene perturbation-related omics dataset | PerturbAtlas | |||||
Description | RNA binding motif protein 8A |
GTO ID | GTC1358 |
Trial ID | NCT01153646 |
Disease | HIV Infection |
Altered gene | TAR|CCR5 |
Therapeutic/Target gene | Target gene |
Therapy | shRNA|Ribozyme |
Treatment | pHIV7-shI-TAR-CCR5RZ |
Phase | Phase1 |
Recruitment status | Terminated |
Title | A Pilot Study of Safety and Feasibility of T-Cell Immunotherapy Using Lentivirus Vector-Expressed RNAi in Autologous T-Cells of HIV-1 Infected Patients Who Have Failed Anti-Retroviral Therapy |
Year | 2010 |
Country | United States |
Company sponsor | City of Hope Medical Center |
Other ID(s) | 03161|IND #14146 |
Vector information | |||||
|
Cohort1: dose level 1 | |||||||||
|
|||||||||
Cohort2: dose level 2 | |||||||||
|