Gene symbol | TERT | Synonyms | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | telomerase reverse transcriptase |
GTO ID | GTC1357 |
Trial ID | NCT01153113 |
Disease | Prostate Cancer |
Altered gene | TERT |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | hTERT mRNA DC |
Phase | Phase1|Phase2 |
Recruitment status | Withdrawn |
Title | Phase II Study of Active Immunotherapy With Mature, Human Telomerase Reverse Transcriptase Messenger RNA -Transfected, Autologous Dendritic Cells (DC) Administered In A Prime-Boost Format to Subjects With Metastatic Prostate Cancer |
Year | 2008 |
Country | United States |
Company sponsor | University of Florida |
Other ID(s) | LAMP hTERT DC Vaccine |
Vector information | |||
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Cohort1: dose level 1_dose level 2 | |||||||||
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Cohort2: dose level 1 | |||||||||
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