Basic Information

Gene symbol FOLH1 Synonyms FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP Type of gene protein-coding
Description folate hydrolase 1

GTO ID GTC1355
Trial ID NCT01140373
Disease Prostate Cancer
Altered gene PSMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment PSMA CAR-T cells
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleAdoptive Transfer of Autologous T Cells Targeted to Prostate Specific Membrane Antigen (PSMA) for the Treatment of Castrate Metastatic Prostate Cancer (CMPC)
Year2010
CountryUnited States
Company sponsorMemorial Sloan Kettering Cancer Center
Other ID(s)09-036

Clinical Result

Cohort 1
Administration route None
Dosage 1E7 cells/kg, 3E7 cells/kg, 1E8 cells/kg
Donor type Autologous
Pts 13
Age Adult, Older_Adult
Lymph depletion Yes

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