Basic Information

Gene symbol HSPB1 Synonyms CMT2F, HEL-S-102, HMN2B, HMND3, HS.76067, HSP27, HSP28, Hsp25, SRP27 Type of gene protein-coding
Description heat shock protein family B (small) member 1

GTO ID GTC1352
Trial ID NCT01120470
Disease Prostate Cancer
Altered gene Hsp27
Therapeutic/Target gene Target gene
TherapyASO
Treatment OGX-427|Apatorsen
Co-treatment Prednisone
PhasePhase2
Recruitment statusCompleted
TitleA Randomized Phase II Study of OGX-427 (a Second-Generation Antisense Oligonucleotide to Heat Shock Protein-27) in Patients With Castration Resistant Prostate Cancer Who Have Not Previously Received Chemotherapy for Metastatic Disease
Year2010
CountryCanada|United States
Company sponsorBritish Columbia Cancer Agency
Other ID(s)PR-01
Vector information
VectorNo vector was used

Clinical Result

Cohort 1
Administration route intravenous infusion
Age Adult, Older_Adult

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