Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | erb-b2 receptor tyrosine kinase 2 |
GTO ID | GTC1350 |
Trial ID | NCT01109095 |
Disease | Brain Glioblastoma Multiforme |
Altered gene | HER2 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | HER2 CAR-T cells |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Completed |
Title | CMV-specific Cytotoxic T Lymphocytes Expressing CAR Targeting HER2 in Patients With GBM |
Year | 2010 |
Country | United States |
Company sponsor | Baylor College of Medicine |
Other ID(s) | H-24487 - HERT GBM |
Cohort 1 | |||||||||
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