Gene symbol | FURIN | Synonyms | FUR, PACE, PCSK3, SPC1 | Type of gene | protein-coding |
Chromosome | 15 | Map location | 15q26.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | furin, paired basic amino acid cleaving enzyme |
Gene symbol | TGFB1 | Synonyms | CED, DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | transforming growth factor beta 1 |
Gene symbol | TGFB2 | Synonyms | G-TSF, LDS4, TGF-beta2 | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1q41 | dbXrefs | |
Description | transforming growth factor beta 2 |
GTO ID | GTC1341 |
Trial ID | NCT01061840 |
Disease | Ewing Sarcoma | Liver Cancer | Lung Non-Small Cell Carcinoma |
Altered gene | FURIN|TGFB1|TGFB2 |
Therapeutic/Target gene | Target gene |
Therapy | shRNA |
Treatment | Vigil|FANG Vaccine |
Phase | Phase1 |
Recruitment status | Completed |
Title | Phase I Trial of Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Vaccine for Advanced Cancer |
Year | 2009 |
Country | United States |
Company sponsor | Gradalis, Inc. |
Other ID(s) | CL-PTL-101 |
Cohort1: Vigil_dose level 2 | |||||||
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Cohort2: Vigil_dose level 3 | |||||||
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Cohort3: Vigil_dose level 1 | |||||||
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