Basic Information

Gene symbol gag Synonyms None Type of gene protein-coding
Description Pr55(Gag)

GTO ID GTC1335
Trial ID NCT00991224
Disease HIV Infection
Altered gene gag
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment WT-gag TCR-T cells|α/6-gag TCR-T cells
HLAHLA-A*02
PhasePhase1
Recruitment statusCompleted
TitleA Pilot, Open Label, Multi Arm, Single Ctr Study to Evaluate Safety & Tolerability of Escalating Doses of Autologous T Cells Modified With Lentiviral Vectors Expressing High Affinity Gag-specific TCRS in HLA-A02 Patients With HIV
Year2009
CountryUnited States
Company sponsorUniversity of Pennsylvania
Other ID(s)810108

Clinical Result

Cohort1: WT-gag
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion No
Cohort2: α/6-gag
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion No

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