Gene symbol | BIRC5 | Synonyms | API4, EPR-1 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q25.3 | dbXrefs | |
Description | baculoviral IAP repeat containing 5 |
Gene symbol | TERT | Synonyms | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | telomerase reverse transcriptase |
Gene symbol | TP53 | Synonyms | BCC7, BMFS5, LFS1, P53, TRP53 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17p13.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | tumor protein p53 |
GTO ID | GTC1334 |
Trial ID | NCT00978913 |
Disease | Breast Cancer | Malignant Adenoma |
Altered gene | BIRC5|TERT|TP53 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | DC Vaccine |
Co-treatment | Cyclophosphamide |
Phase | Phase1 |
Recruitment status | Completed |
Title | Evaluation of Dendritic Cells Transfected With Survivin, hTERT and p53 mRNA as a Treatment for Patients With Metastatic Breast Cancer or Malignant Melanoma |
Year | 2009 |
Country | Denmark |
Company sponsor | Inge Marie Svane |
Other ID(s) | AA 0914 |
Vector information | |||
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Cohort 1 | |||||||||
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