Basic Information

Gene symbol BIRC5 Synonyms API4, EPR-1 Type of gene protein-coding
Description baculoviral IAP repeat containing 5

Gene symbol TERT Synonyms CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description telomerase reverse transcriptase

Gene symbol TP53 Synonyms BCC7, BMFS5, LFS1, P53, TRP53 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description tumor protein p53

GTO ID GTC1334
Trial ID NCT00978913
Disease Breast Cancer | Malignant Adenoma
Altered gene BIRC5|TERT|TP53
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment DC Vaccine
Co-treatment Cyclophosphamide
PhasePhase1
Recruitment statusCompleted
TitleEvaluation of Dendritic Cells Transfected With Survivin, hTERT and p53 mRNA as a Treatment for Patients With Metastatic Breast Cancer or Malignant Melanoma
Year2009
CountryDenmark
Company sponsorInge Marie Svane
Other ID(s)AA 0914
Vector information
Vectordendritic cell

Clinical Result

Cohort 1
Administration route intradermal injection
Dosage 1E6 cells
Pts 31
Age Adult, Older_Adult

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