Gene symbol | WT1 | Synonyms | AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11p13 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | WT1 transcription factor |
GTO ID | GTC1330 |
Trial ID | NCT00965224 |
Disease | Acute Myeloid Leukemia | Multiple Myeloma | Chronic Myeloid Leukemia |
Altered gene | WT1 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | DC Vaccine |
Phase | Phase2 |
Recruitment status | Unknown |
Title | Therapeutic Efficacy of Wilms Tumor Gene (WT1) mRNA-electroporated Autologous Dendritic Cell Vaccination in Patients With Myeloid Malignancies and Multiple Myeloma: A Phase II Trial |
Year | 2010 |
Country | Belgium |
Company sponsor | University Hospital, Antwerp |
Other ID(s) | CCRG 09-003 |
Vector information | |||
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Cohort1: Male | |||||||||||
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Cohort2: Female | |||||||||||
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