Basic Information

Gene symbol BIRC5 Synonyms API4, EPR-1 Type of gene protein-coding
Description baculoviral IAP repeat containing 5

Gene symbol TERT Synonyms CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description telomerase reverse transcriptase

GTO ID GTC1329
Trial ID NCT00961844
Disease Malignant Adenoma
Altered gene TERT|BIRC5
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment DC Vaccine
Co-treatment Temozolomide
PhasePhase1|Phase2
Recruitment statusTerminated
TitlePhase I/II Trial for Vaccine Therapy With Dendritic Cells - Transfected With hTERT-, Survivin- and Tumor Cell Derived mRNA + ex Vivo T Cell Expansion and Reinfusion in Patients With Metastatic Malignant Melanoma
Year2009
CountryNorway
Company sponsorSteinar Aamdal
Other ID(s)DC-004|2008-006253-41
Vector information
Vectordendritic cell

Clinical Result

Cohort 1
Administration route None
Pts 15
Age Adult, Older_Adult

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