Gene symbol | PMEL | Synonyms | D12S53E, HMB-45, HMB45, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV, gp100 | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12q13.2 | dbXrefs | |
Description | premelanosome protein |
Gene symbol | TYR | Synonyms | ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q14.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | tyrosinase |
GTO ID | GTC1325 |
Trial ID | NCT00929019 |
Disease | Uveal Melanoma |
Altered gene | gp100|TYR |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | mRNA Transfected Dendritic Cell Vaccination |
Phase | Phase1|Phase2 |
Recruitment status | Terminated |
Title | MRNA Transfected Dendritic Cell Vaccination in High Risk Uveal Melanoma Patients |
Year | 2009 |
Country | Netherlands |
Company sponsor | Radboud University Medical Center |
Other ID(s) | NL22553.000.08|KUN2008-035 |
Vector information | |||
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Cohort1: dendritic cell vaccination | |||||||
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Cohort2: No Intervention | |||||||
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