Basic Information

Gene symbol ERBB2 Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description erb-b2 receptor tyrosine kinase 2

GTO ID GTC1323
Trial ID NCT00924287
Disease Metastatic Cancer
Altered gene HER2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment HER2 CAR-T cells
PhasePhase1|Phase2
Recruitment statusTerminated
TitleGene Therapy Using Anti-Her-2 Cells to Treat Metastatic Cancer
Year2009
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)090041|09-C-0041
Vector information
Vectorretrovirus
Transgene/Inserted geneanti-Her-2 gene

Clinical Result

Cohort 1
Administration route None
Pts 1
Age Adult, Older_Adult
Lymph depletion Yes

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