Gene symbol | TNFSF10 | Synonyms | APO2L, Apo-2L, CD253, TANCR, TL2, TNLG6A, TRAIL | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q26.31 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | TNF superfamily member 10 |
GTO ID | GTC1322 |
Trial ID | NCT00923390 |
Disease | Renal Carcinoma | Kidney Cancer |
Altered gene | TRAIL |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | 2G-1 TCR-T cells |
Phase | Phase1 |
Recruitment status | Terminated |
Title | Phase 1/2 Study of Metastatic Renal Cancer Using T-Cells Transduced With a T-Cell Receptor Which Recognizes TRAIL Bound to the DR4 Receptor |
Year | 2009 |
Country | United States |
Company sponsor | National Cancer Institute (NCI) |
Other ID(s) | 090092|09-C-0092 |
Vector information | |||
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Cohort 1 | |||||||||
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