Basic Information

Gene symbol TNFSF10 Synonyms APO2L, Apo-2L, CD253, TANCR, TL2, TNLG6A, TRAIL Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description TNF superfamily member 10

GTO ID GTC1322
Trial ID NCT00923390
Disease Renal Carcinoma | Kidney Cancer
Altered gene TRAIL
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment 2G-1 TCR-T cells
PhasePhase1
Recruitment statusTerminated
TitlePhase 1/2 Study of Metastatic Renal Cancer Using T-Cells Transduced With a T-Cell Receptor Which Recognizes TRAIL Bound to the DR4 Receptor
Year2009
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)090092|09-C-0092
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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