Basic Information

Gene symbol BIRC5 Synonyms API4, EPR-1 Type of gene protein-coding
Description baculoviral IAP repeat containing 5

Gene symbol CTAG1B Synonyms CT6.1, CTAG, CTAG1, ESO1, LAGE-2, LAGE2B, NY-ESO-1 Type of gene protein-coding
Description cancer/testis antigen 1B

Gene symbol MAGEC1 Synonyms CT7, CT7.1 Type of gene protein-coding
Description MAGE family member C1

Gene symbol MAGEC2 Synonyms CT10, HCA587, MAGEE1 Type of gene protein-coding
Description MAGE family member C2

Gene symbol TPBG Synonyms 5T4, 5T4AG, M6P1, WAIF1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description trophoblast glycoprotein

GTO ID GTC1321
Trial ID NCT00923312
Disease Lung Non-Small Cell Carcinoma
Altered gene CTAG1B|MAGE-C1|MAGE-C2|BIRC5|TPBG
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment CV9201
PhasePhase1|Phase2
Recruitment statusCompleted
TitleSafety and Efficacy Phase I/IIa Trial of an RNActive-Derived Cancer Vaccine in Stage IIIB/IV Non Small Cell Lung Cancer (NSCLC)
Year2009
CountryGermany|Switzerland
Company sponsorCureVac
Other ID(s)CV-9201-003
Vector information
Vectorprotamine

Clinical Result

Cohort 1
Administration route None
Pts 46
Age Adult, Older_Adult
References PMID: 21150709

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