Gene symbol | BIRC5 | Synonyms | API4, EPR-1 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q25.3 | dbXrefs | |
Description | baculoviral IAP repeat containing 5 |
Gene symbol | CTAG1B | Synonyms | CT6.1, CTAG, CTAG1, ESO1, LAGE-2, LAGE2B, NY-ESO-1 | Type of gene | protein-coding |
Chromosome | X | Map location | Xq28 | dbXrefs | |
Description | cancer/testis antigen 1B |
Gene symbol | MAGEC1 | Synonyms | CT7, CT7.1 | Type of gene | protein-coding |
Chromosome | X | Map location | Xq27.2 | dbXrefs | |
Description | MAGE family member C1 |
Gene symbol | MAGEC2 | Synonyms | CT10, HCA587, MAGEE1 | Type of gene | protein-coding |
Chromosome | X | Map location | Xq27.2 | dbXrefs | |
Description | MAGE family member C2 |
Gene symbol | TPBG | Synonyms | 5T4, 5T4AG, M6P1, WAIF1 | Type of gene | protein-coding |
Chromosome | 6 | Map location | 6q14.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | trophoblast glycoprotein |
GTO ID | GTC1321 |
Trial ID | NCT00923312 |
Disease | Lung Non-Small Cell Carcinoma |
Altered gene | CTAG1B|MAGE-C1|MAGE-C2|BIRC5|TPBG |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | CV9201 |
Phase | Phase1|Phase2 |
Recruitment status | Completed |
Title | Safety and Efficacy Phase I/IIa Trial of an RNActive-Derived Cancer Vaccine in Stage IIIB/IV Non Small Cell Lung Cancer (NSCLC) |
Year | 2009 |
Country | Germany|Switzerland |
Company sponsor | CureVac |
Other ID(s) | CV-9201-003 |
Vector information | |||
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Cohort 1 | |||||||||
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