Detail

Basic Information Clinical Results Relationship Graph

Basic Information

Gene symbol	LAMP3	Synonyms	CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403	Type of gene	protein-coding
Chromosome	3	Map location	3q27.1	dbXrefs
Gene perturbation-related omics dataset	PerturbAtlas
Description	lysosomal associated membrane protein 3

Gene symbol	UL83	Synonyms	None	Type of gene	protein-coding
Chromosome	-	Map location	NC_006273.2	dbXrefs
Description	tegument protein pp65

GTO ID	GTC1291
Trial ID	NCT00639639
Disease	Brain Neoplasm
Altered gene	UL83\|LAMP
Therapeutic/Target gene	Therapeutic gene
Therapy	mRNA vaccine
Treatment	CMV pp65-LAMP mRNA-loaded DC Vaccine
Co-treatment	CMV-ALT
Phase	Phase1
Recruitment status	Completed
Title	Anti-Tumor Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed Glioblastoma Multiforme During Recovery From Therapeutic Temozolomide-induced Lymphopenia
Year	2006
Country	United States
Company sponsor	Gary Archer Ph.D.
Other ID(s)	Pro00003877\|CDR0000589624\|DUMC-8108-07-1R1\|Discretionary Funds

Vector information

Vector	dendritic cell

Clinical Result

Cohort1: CMV-DC_CMV-ALT

Administration route	intravenous injection\|intradermal injection
Dosage	CMV-DC vaccine, every 1-3 weeks for up to 3 doses
Age	Adult, Older_Adult
References	PMID: 32719000

Cohort2: CMV-DC

Administration route	intradermal injection
Dosage	CMV-DC vaccine, every 1-3 weeks for up to 3 doses
Age	Adult, Older_Adult
References	PMID: 32719000

Cohort3: indium In 111-labeled CMV-DC

Administration route	intradermal injection
Dosage	indium In 111-labeled CMV-DC
Age	Adult, Older_Adult
References	PMID: 32719000

Cohort4: CMV-DC_tetanus toxoid

Administration route	intradermal injection
Dosage	111 In-labeled CMV-DC
Age	Adult, Older_Adult
References	PMID: 32719000

Relationship Graph

Overview of Knowledge Graph