Gene symbol | TNF | Synonyms | DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F | Type of gene | protein-coding |
Chromosome | 6 | Map location | 6p21.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | tumor necrosis factor |
GTO ID | GTC1286 |
Trial ID | NCT00617032 |
Disease | Rheumatoid Arthritis |
Altered gene | TNF |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | tgAAC94 |
Phase | Phase1 |
Recruitment status | Completed |
Title | A Phase 1 Dose Escalation Study of Intra-Articular Administration of tgAAC94, a Recombinant Adeno-Associated Vector Containing the TNFR:Fc Fusion Gene, in Inflammatory Arthritis |
Year | 2008 |
Country | Canada|United States |
Company sponsor | Targeted Genetics Corporation |
Other ID(s) | 13E04|RAC Protocol # 0307-588|HPB 0088676 |
Vector information | |||||||||
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Cohort1: dose level 1 | |||||||||
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Cohort2: dose level 2 | |||||||||
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