Gene symbol | BCL2 | Synonyms | Bcl-2, PPP1R50 | Type of gene | protein-coding |
Chromosome | 18 | Map location | 18q21.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | BCL2 apoptosis regulator |
GTO ID | GTC1279 |
Trial ID | NCT00543205 |
Disease | Melanoma |
Altered gene | Bcl-2 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | Genasense|G3139|oblimersen sodium |
Phase | Phase2|Phase3 |
Recruitment status | Terminated |
Title | A Pharmacokinetic Study of Genasense (Bcl-2 Antisense Oligonucleotide) in Combination With Dacarbazine (DTIC) in Subjects With Advanced Melanoma and Normal or Impaired Hepatic Function |
Year | 2007 |
Country | United States |
Company sponsor | Genta Incorporated |
Other ID(s) | GPK103 |
Vector information | |||
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Cohort 1 | |||||
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