Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC1278
Trial ID NCT00531336
Disease Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
Co-treatment Avastin
PhasePhase2
Recruitment statusCompleted
TitleComparison of Combined Therapy of Intravitreal Injection of Avastin and Macugen Versus Mono-Therapy The MAAM Study - a Pilot Study
Year2006
CountryAustria
Company sponsorThe Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Other ID(s)EK06-001839-18

Clinical Result

Cohort1: pegaptanib_Avastin
Administration route intravitreal injection
Dosage 0.3 mg, every 6 weeks as long as required
Age Adult, Older_Adult
Cohort2: Avastin
Administration route intravitreal injection
Dosage 0 mg
Age Adult, Older_Adult
Cohort3: pegaptanib
Administration route intravitreal injection
Dosage 0.3 mg, every 6 weeks as long as required
Age Adult, Older_Adult

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