Basic Information

Gene symbol CD40LG Synonyms CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD40 ligand

GTO ID GTC1272
Trial ID NCT00504322
Disease Esophageal Cancer
Altered gene CD40LG
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment AdcuCD40L
PhasePhase1|Phase2
Recruitment statusWithdrawn
TitlePhase II, Randomized, Double-blinded, Placebo-Control, Toxicity/Efficacy Study on the Transfer of Adenovirus With the CD40 Ligand Gene (AdcuCD40L) to Patients With Stage I, II or III Esophageal Carcinoma
Year2007
CountryUnited States
Company sponsorWeill Medical College of Cornell University
Other ID(s)502007770
Vector information
Vectoradenovirus
ConstructAdcuCD40L
Vector typeadenoviral vector
Transgene/Inserted genehuman CD40 ligand (CD40L) gene

Clinical Result

Cohort 1
Administration route intratumoral injection
Pts 0
Age Adult, Older_Adult

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