Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC1268
Trial ID NCT00446381
Disease Diabetic Macular Edema | Proliferative Diabetic Retinopathy
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
PhaseNot Applicable
Recruitment statusCompleted
TitleEffect of Macugen (Pegaptanib) on Surgical Outcomes and Growth Factors Including Vascular Endothelial Growth Factor (VEGF) Levels in Patients With Proliferative Diabetic Retinopathy (PDR) and Clinically Significant Diabetic Macular Edema (CSDME)
Year2006
CountryCanada
Company sponsorLawson Health Research Institute
Other ID(s)R-06-821|Health Canada Control #108753

Clinical Result

Cohort1: Patients with Proliferative Diabetic Retinopathy
Administration route intravitreal injection
Dosage Pegaptanib, 0.3 mg, once pre-operatively
Age Adult, Older_Adult
Cohort2: Patients with Clinically Significant Macular Edema
Administration route intravitreal injection
Dosage Pegaptanib, 0.3 mg, once pre-operatively
Age Adult, Older_Adult

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