Gene symbol | XIAP | Synonyms | API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | Type of gene | protein-coding | |
Chromosome | X | Map location | Xq25 | dbXrefs | Entrez:331 MIM:300079 HGNC:HGNC:592 Ensembl:ENSG00000101966 AllianceGenome:HGNC:592 | |
Gene perturbation-related omics dataset | PertOrg | |||||
Description | X-linked inhibitor of apoptosis |
GTO ID | GTC1258 |
Trial ID | NCT00363974 |
Disease | Acute Myeloid Leukemia |
Altered gene | XIAP |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | AEG35156 |
Phase | Phase1|Phase2 |
Recruitment status | Completed |
Title | An Open-Label Phase I/II Study of XIAP Antisense AEG35156 Administered to Patients With Refractory/Relapsed AML in Combination With Chemotherapy |
Year | 2006 |
Country | Canada|United States |
Company sponsor | Aegera Therapeutics |
Other ID(s) | AEG35156-103|MDA 2005-0384|PMH 05-0452-C |
Vector information | |||
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Cohort 1 | |||||
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