Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC1254
Trial ID NCT00354445
Disease Age-Related Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
PhasePhase4
Recruitment statusUnknown
TitleA Phase IV, Open Label, Multi-Center, Study of Maintenance Intravitreous Injections of Macugen (Pegaptanib Sodium) Given Every 6 Weeks for 48 Weeks in Subjects With Subfoveal Neovascular Age-Related Macular Degeneration (AMD) Initially Treated With a Modality Resulting in Maculopathy Improvement
Year2006
CountryUnited States
Company sponsorEyetech Pharmaceuticals
Other ID(s)EOP1023

Clinical Result

Cohort 1
Administration route intravitreal injection
Dosage pegaptanib, 0.3 mg, every 6 weeks for 48 weeks with follow-up to week 54
Pts 487
Age Adult, Older_Adult
References PMID: 20472746

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