Basic Information

Gene symbol CD40LG Synonyms CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD40 ligand

GTO ID GTC1252
Trial ID NCT00328887
Disease Esophageal Cancer
Altered gene CD40LG
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment AdcuCD40L
PhasePhase1
Recruitment statusWithdrawn
TitlePhase I, Initial Safety/Toxicity Study on the Transfer of Adenovirus With the CD40 Ligand Gene (AdCUCD40L) to Patients With Stage III or IV Esophageal Carcinoma
Year2006
CountryUnited States
Company sponsorWeill Medical College of Cornell University
Other ID(s)0011004683|5 R01 CA10198-02
Vector information
Vectoradenovirus
ConstructAdcuCD40L
Vector typeadenoviral vector
Transgene/Inserted genehuman CD40 ligand (CD40L) gene

Clinical Result

Cohort 1
Administration route intratumoral injection
Pts 0
Age Adult, Older_Adult

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