Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC1251
Trial ID NCT00321997
Disease Age-Related Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
PhasePhase2|Phase3
Recruitment statusCompleted
TitleA Phase Ii/Iii Randomized, Double-Masked, Controlled, Dose-Ranging, Multi-Center Comparative Trial, In Parallel Groups, To Establish The Safety And Efficacy Of Intravitreal Injections Of Eye001 (Anti-Vegf Pegylated Aptamer) Given Every 6 Weeks For 54 Weeks, In Patients With Exudative Age-Related Macular Degeneration (Amd)
Year2006
CountryUnited States
Company sponsorEyetech Pharmaceuticals
Other ID(s)EOP1003 and EOP1004

Clinical Result

Cohort 1
Administration route intravitreal injection
Dosage 0.3 mg
Age Adult, Older_Adult
References PMID: 24997182

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