Basic Information

Gene symbol TKT Synonyms HEL-S-48, HEL107, SDDHD, TK, TKT1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description transketolase

GTO ID GTC1247
Trial ID NCT00300521
Disease Hepatocellular Carcinoma
Altered gene tk
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment AdV-TK
PhasePhase2
Recruitment statusCompleted
TitleLiver Transplantation With ADV-TK Gene Therapy Improves Survival in Patients With Advanced Hepatocellular Carcinoma
Year2006
CountryChina
Company sponsorBeijing Chao Yang Hospital
Other ID(s)LT2000-09
Vector information
Vectoradenovirus
ConstructAdV-TK
Vector typeadenoviral vector
Transgene/Inserted geneherpes simplex virus (HSV) thymidine kinase gene

Clinical Result

Cohort 1
Administration route None
Age Child, Adult, Older_Adult
References PMID: 31769427

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