Gene symbol | BCL2 | Synonyms | Bcl-2, PPP1R50 | Type of gene | protein-coding |
Chromosome | 18 | Map location | 18q21.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | BCL2 apoptosis regulator |
GTO ID | GTC1244 |
Trial ID | NCT00285103 |
Disease | Chronic Lymphocytic Leukemia |
Altered gene | Bcl-2 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | SPC2996 |
Phase | Phase1|Phase2 |
Recruitment status | Completed |
Title | An Open-labelled, International, Multicenter, Dose Escalating, Phase I/II Study of SPC2996,an LNA Antisense Molecule Against Bcl-2, in Patients With Relapsed or Refractory Chronic Lymphocytic Leukaemia |
Year | 2005 |
Country | United States|Denmark|France|United Kingdom |
Company sponsor | Santaris Pharma A/S |
Other ID(s) | SPC2996-101 |
Vector information | |||
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Cohort 1 | |||||||
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