Basic Information

Gene symbol CEACAM5 Synonyms CD66e, CEA Type of gene protein-coding
Description CEA cell adhesion molecule 5

GTO ID GTC1237
Trial ID NCT00228189
Disease Colorectal Cancer
Altered gene CEA
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
PhasePhase1|Phase2
Recruitment statusCompleted
TitleInduction of Specific T Cell Responses in Colorectal Cancer Patients With Liver Metastases Upon Vaccination With Autologous Dendritic Cells Pulsed With CEA-peptide or Electroporated With CEA-RNA: Evaluation of in Vivo Immune Response.
Year2003
CountryNetherlands
Company sponsorRadboud University Medical Center
Other ID(s)920-03-250|NWO920-03-250
Vector information
Vectordendritic cell

Clinical Result

Cohort1: CEA-peptide
Administration route intradermal injection
Pts 11
Age Adult, Older_Adult
References PMID: 21187495
Cohort2: CEA-mRNA
Administration route intradermal injection
Pts 5
Age Adult, Older_Adult
References PMID: 21187495

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