Gene symbol | CD40LG | Synonyms | CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L | Type of gene | protein-coding |
Chromosome | X | Map location | Xq26.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD40 ligand |
Gene symbol | IL2 | Synonyms | IL-2, TCGF, lymphokine | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4q27 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | interleukin 2 |
GTO ID | GTC1236 |
Trial ID | NCT00224354 |
Disease | Chronic Lymphocytic Leukemia |
Altered gene | IL-2|CD40L |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | IL-2/hCD40L gene-modified B-CLL cells |
Phase | Phase1 |
Recruitment status | Withdrawn |
Title | Treatment of Chronic Lymphocytic B-Leukemia (B-CLL) With Human IL-2 Gene Modified and Human CD40 Ligand-Expressing Autologous Tumor Cells After Depletion of Regulatory T Cells |
Year | 2005 |
Country | United States |
Company sponsor | Baylor College of Medicine |
Other ID(s) | 17656|CLONTAK |
Cohort 1 | |||||||||||
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