Gene symbol | VEGFA | Synonyms | L-VEGF, MVCD1, VEGF, VPF | Type of gene | protein-coding |
Chromosome | 6 | Map location | 6p21.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | vascular endothelial growth factor A |
GTO ID | GTC1235 |
Trial ID | NCT00215670 |
Disease | Age-Related Macular Degeneration |
Altered gene | VEGFA |
Therapeutic/Target gene | Target gene |
Therapy | Aptamer |
Treatment | Macugen|pegaptanib|EYE001 |
Phase | Phase2|Phase3 |
Recruitment status | Completed |
Title | A Randomized, Double-Masked, Multi-Center Trial of the Safety, Tolerability and Pharmacokinetics of 1 Mg/Eye and 3 Mg/Eye Intravitreal Injections of Pegaptanib Sodium (Anti-Vegf Pegylated Aptamer) Given Every 6 Weeks for 54 Weeks, in Patients With Exudative Age-Related Macular Degeneration (AMD) |
Year | 2005 |
Country | United States |
Company sponsor | Eyetech Pharmaceuticals |
Other ID(s) | EOP1006 |
Cohort1: dose level 1 | |||||||
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Cohort2: dose level 2 | |||||||
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