Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC1232
Trial ID NCT00134667
Disease Age-Related Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
Co-treatment Photodynamic Therapy (PDT) with Visudyne (verteporfin)
PhasePhase4
Recruitment statusTerminated
TitleA Phase IIIb/IV Randomized, Double-Masked, Active Controlled, Dose-Ranging, Multi-Center Comparative Trial, in Parallel Groups, to Compare the Safety and Efficacy of Intravitreal Injections of Pegaptanib Sodium (Macugen) Given Every 6 Weeks for 102 Weeks, to Pegaptanib Sodium Plus Photodynamic Therapy (PDT) With Visudyne, in Patients With Exudative Age-Related Macular Degeneration (AMD)
Year2005
CountryUnited States
Company sponsorEyetech Pharmaceuticals
Other ID(s)EOP1012

Clinical Result

Cohort 1
Administration route intravitreal injection
Pts 360
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph