Gene symbol | VEGFA | Synonyms | L-VEGF, MVCD1, VEGF, VPF | Type of gene | protein-coding |
Chromosome | 6 | Map location | 6p21.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | vascular endothelial growth factor A |
GTO ID | GTC1232 |
Trial ID | NCT00134667 |
Disease | Age-Related Macular Degeneration |
Altered gene | VEGFA |
Therapeutic/Target gene | Target gene |
Therapy | Aptamer |
Treatment | Macugen|pegaptanib|EYE001 |
Co-treatment | Photodynamic Therapy (PDT) with Visudyne (verteporfin) |
Phase | Phase4 |
Recruitment status | Terminated |
Title | A Phase IIIb/IV Randomized, Double-Masked, Active Controlled, Dose-Ranging, Multi-Center Comparative Trial, in Parallel Groups, to Compare the Safety and Efficacy of Intravitreal Injections of Pegaptanib Sodium (Macugen) Given Every 6 Weeks for 102 Weeks, to Pegaptanib Sodium Plus Photodynamic Therapy (PDT) With Visudyne, in Patients With Exudative Age-Related Macular Degeneration (AMD) |
Year | 2005 |
Country | United States |
Company sponsor | Eyetech Pharmaceuticals |
Other ID(s) | EOP1012 |
Cohort 1 | |||||||
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