Gene symbol | TNF | Synonyms | DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F | Type of gene | protein-coding |
Chromosome | 6 | Map location | 6p21.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | tumor necrosis factor |
GTO ID | GTC1231 |
Trial ID | NCT00126724 |
Disease | Ankylosing Spondylitis | Rheumatoid Arthritis | Psoriatic Arthritis |
Altered gene | TNF |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | tgAAC94 |
Phase | Phase1|Phase2 |
Recruitment status | Completed |
Title | A Phase I/II Study of Repeat Intra-articular Administration of tgAAC94, a Recombinant Adeno-Associated Vector Containing the TNFR:Fc Fusion Gene, in Inflammatory Arthritis Subjects With and Without Concurrent TNF-alpha Antagonists |
Year | 2005 |
Country | United States |
Company sponsor | Targeted Genetics Corporation |
Other ID(s) | 13G01|NIH Protocol Number: 0504-705 |
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