Basic Information

Gene symbol CCNG1 Synonyms CCNG Type of gene protein-coding
Description cyclin G1

GTO ID GTC1230
Trial ID NCT00121745
Disease Pancreatic Cancer
Altered gene CCNG1
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment Rexin-G
PhasePhase1
Recruitment statusTerminated
TitlePhase I Evaluation of Safety of Intravenous Infusion of a Pathotropic Vector Bearing a Cytocidal Cyclin G1 Construct (Rexin-G) as Intervention for Locally Advanced and Metastatic Pancreatic Cancer Refractory to Standard Chemotherapy
Year2005
CountryUnited States
Company sponsorEpeius Biotechnologies
Other ID(s)MC044C
Vector information
Vectorretrovirus

Clinical Result

Cohort1: dose level 1
Administration route intravenous infusion
Dosage 7.5E9 cfu 500 ml
Age Adult, Older_Adult
Cohort2: dose level 2
Administration route intravenous infusion
Dosage 1.1E10 cfu 500 ml
Age Adult, Older_Adult
Cohort3: dose level 3
Administration route intravenous infusion
Dosage 3.E10 cfu 500 ml
Age Adult, Older_Adult
Cohort4: dose level 4
Administration route intravenous infusion
Dosage 8E10 cfu 500 ml
Age Adult, Older_Adult

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