Basic Information

Gene symbol RAF1 Synonyms CMD1NN, CRAF, NS5, Raf-1, c-Raf Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description Raf-1 proto-oncogene, serine/threonine kinase

GTO ID GTC1225
Trial ID NCT00100672
Disease Neoplasm
Altered gene C-Raf
Therapeutic/Target gene Target gene
TherapyASO
Treatment LErafAON-ETU
PhasePhase1
Recruitment statusCompleted
TitlePhase I Study of an Easy-to-Use Intravenous Formulation of Liposome Entrapped C-raf Antisense Oligonucleotide (LErafAON-ETU) Administered on a Weekly Schedule in Patients With Advanced Cancer
Year2005
CountryUnited States
Company sponsorINSYS Therapeutics Inc
Other ID(s)LErafAON-ETU-104-R02
Vector information
VectorNo vector was used

Clinical Result

Cohort 1
Administration route intravenous infusion
Age Adult, Older_Adult

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