Gene symbol | RRM2 | Synonyms | C2orf48, R2, RR2, RR2M | Type of gene | protein-coding |
Chromosome | 2 | Map location | 2p25.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | ribonucleotide reductase regulatory subunit M2 |
GTO ID | GTC1220 |
Trial ID | NCT00084643 |
Disease | Rectal Cancer | Colon Cancer |
Altered gene | RRM2 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | GTI-2040 |
Co-treatment | oxaliplatin|capecitabine|pharmacological study|laboratory biomarker analysis |
Phase | Phase1 |
Recruitment status | Completed |
Title | A Phase I Study of GTI-2040 in Combination With Oxaliplatin and Capecitabine in Patients With Advanced Metastatic Solid Tumors |
Year | 2004 |
Country | United States |
Company sponsor | National Cancer Institute (NCI) |
Other ID(s) | NCI-2012-03077|PHI-41|U01CA062505|CDR0000365466 |
Vector information | |||
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Cohort 1 | |||||||||
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