Gene symbol | BCL2 | Synonyms | Bcl-2, PPP1R50 | Type of gene | protein-coding |
Chromosome | 18 | Map location | 18q21.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | BCL2 apoptosis regulator |
GTO ID | GTC1211 |
Trial ID | NCT00070083 |
Disease | Lymphoma |
Altered gene | Bcl-2 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | Genasense|G3139|oblimersen sodium |
Co-treatment | rituximab|cyclophosphamide|doxorubicin hydrochloride|prednisone|vincristine sulfate |
Phase | Phase1 |
Recruitment status | Completed |
Title | A Phase I Study Of G3139 Antisense Oligonucleotide (Oblimersen) In Combination With CHOP And Rituximab In Untreated Advanced Stage Diffuse Large B Cell Lymphoma |
Year | 2003 |
Country | United States|Canada |
Company sponsor | British Columbia Cancer Agency |
Other ID(s) | CDR0000329985|BCCA-NCI-5818|NCI-5818 |
Vector information | |||
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Cohort 1 | |||||
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