Basic Information

Gene symbol BCL2 Synonyms Bcl-2, PPP1R50 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description BCL2 apoptosis regulator

GTO ID GTC1211
Trial ID NCT00070083
Disease Lymphoma
Altered gene Bcl-2
Therapeutic/Target gene Target gene
TherapyASO
Treatment Genasense|G3139|oblimersen sodium
Co-treatment rituximab|cyclophosphamide|doxorubicin hydrochloride|prednisone|vincristine sulfate
PhasePhase1
Recruitment statusCompleted
TitleA Phase I Study Of G3139 Antisense Oligonucleotide (Oblimersen) In Combination With CHOP And Rituximab In Untreated Advanced Stage Diffuse Large B Cell Lymphoma
Year2003
CountryUnited States|Canada
Company sponsorBritish Columbia Cancer Agency
Other ID(s)CDR0000329985|BCCA-NCI-5818|NCI-5818
Vector information
VectorNo vector was used

Clinical Result

Cohort 1
Administration route None
Age Adult, Older_Adult

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