Basic Information

Gene symbol IL2 Synonyms IL-2, TCGF, lymphokine Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description interleukin 2

Gene symbol XCL1 Synonyms ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1 Type of gene protein-coding
Description X-C motif chemokine ligand 1

GTO ID GTC1207
Trial ID NCT00062855
Disease Neuroblastoma
Altered gene XCL1|IL-2
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment XCL1/IL-2 Ad Neuroblastoma cells
PhasePhase1
Recruitment statusCompleted
TitlePhase I Study of Chemokine and Cytokine Gene Modified Autologous Neuroblastoma Cells for Treatment of Relapsed/Refractory Neuroblastoma Using an Adenoviral Vector (CYCHE)
Year2003
CountryUnited States
Company sponsorBaylor College of Medicine
Other ID(s)H6442|Cyche
Vector information
Vectoradenovirus
Transgene/Inserted genethe lymphotactin and the IL-2 gene

Clinical Result

Cohort 1
Administration route injection
Donor type autologous
Age Child, Adult
References PMID: 17471169

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