Gene symbol | BCL2 | Synonyms | Bcl-2, PPP1R50 | Type of gene | protein-coding |
Chromosome | 18 | Map location | 18q21.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | BCL2 apoptosis regulator |
GTO ID | GTC1200 |
Trial ID | NCT00054548 |
Disease | Advanced Solid Tumor |
Altered gene | Bcl-2 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | Genasense|G3139|oblimersen sodium |
Co-treatment | paclitaxe |
Phase | Phase1 |
Recruitment status | Completed |
Title | A Phase I Study of Antisense Bcl-2 Oligonucleotide (G3139) in Combination With Carboplatin and Paclitaxel in Patients With Advanced Solid Tumors |
Year | 2003 |
Country | United States |
Company sponsor | National Cancer Institute (NCI) |
Other ID(s) | NCI-2013-00010|CO 02904|NCI-5912|WCCC-CO-02904|U01CA062491 |
Vector information | |||
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Cohort 1 | |||||
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