| Gene symbol | TNF | Synonyms | DIF, TNF-alpha, TNFA, TNFSF2, TNLG1F | Type of gene | protein-coding |
| Chromosome | 6 | Map location | 6p21.33 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | tumor necrosis factor | ||||
| GTO ID | GTC1197 |
| Trial ID | NCT00048321 |
| Disease | Rheumatoid Arthritis |
| Altered gene | TNF |
| Therapeutic/Target gene | Target gene |
| Therapy | ASO |
| Treatment | ISIS 104838 |
| Phase | Phase2 |
| Recruitment status | Completed |
| Title | ISIS 104838-CS7, A Double-Blind, Placebo-Controlled, Randomized Trial of the Safety, Efficacy and Pharmacokinetic Profile of ISIS 104838 (TNF-alpha Antisense Oligonucleotide) Subcutaneous Injections in Active Rheumatoid Arthritis Patients |
| Year | 2002 |
| Country | United States|Canada |
| Company sponsor | Ionis Pharmaceuticals, Inc. |
| Other ID(s) | ISIS 104838-CS7 |
| Vector information | |||
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| Cohort 1 | |||||
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