Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC1195
Trial ID NCT00040313
Disease Diabetic Macular Edema
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
PhasePhase2
Recruitment statusCompleted
TitleA Phase II Randomized, Controlled, Double-Masked, Dose-Finding, Multi-Center, Comparative Trial, in Parallel Groups, to Establish the Safety and Preliminary Efficacy of Intravitreal Injections of EYE001 (Anti-VEGF Pegylated Aptamer), Given Every 6 Weeks for 12 to 30 Weeks to Patients With Clinically Significant Diabetic Macular Edema (CSME) Involving the Center of the Macula
Year2002
CountryUnited States
Company sponsorEyetech Pharmaceuticals
Other ID(s)EOP1005

Clinical Result

Cohort 1
Administration route intravitreal injection
Dosage EYE001, Every 6 Weeks for 12 to 30 Weeks
Pts 0
Age Adult, Older_Adult

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