Gene symbol | VEGFA | Synonyms | L-VEGF, MVCD1, VEGF, VPF | Type of gene | protein-coding |
Chromosome | 6 | Map location | 6p21.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | vascular endothelial growth factor A |
GTO ID | GTC1195 |
Trial ID | NCT00040313 |
Disease | Diabetic Macular Edema |
Altered gene | VEGFA |
Therapeutic/Target gene | Target gene |
Therapy | Aptamer |
Treatment | Macugen|pegaptanib|EYE001 |
Phase | Phase2 |
Recruitment status | Completed |
Title | A Phase II Randomized, Controlled, Double-Masked, Dose-Finding, Multi-Center, Comparative Trial, in Parallel Groups, to Establish the Safety and Preliminary Efficacy of Intravitreal Injections of EYE001 (Anti-VEGF Pegylated Aptamer), Given Every 6 Weeks for 12 to 30 Weeks to Patients With Clinically Significant Diabetic Macular Edema (CSME) Involving the Center of the Macula |
Year | 2002 |
Country | United States |
Company sponsor | Eyetech Pharmaceuticals |
Other ID(s) | EOP1005 |
Cohort 1 | |||||||||
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