Basic Information

Gene symbol RAF1 Synonyms CMD1NN, CRAF, NS5, Raf-1, c-Raf Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description Raf-1 proto-oncogene, serine/threonine kinase

GTO ID GTC1188
Trial ID NCT00024648
Disease Neoplasm
Altered gene RAF1
Therapeutic/Target gene Target gene
TherapyASO
Treatment LErafAON
PhasePhase1
Recruitment statusCompleted
TitlePhase I Study to Determine the Maximum Tolerated Dose of LErafAON in Combination With Radiotherapy in Patients With Advanced Malignancies
Year2001
CountryUnited States
Company sponsorINSYS Therapeutics Inc
Other ID(s)LErafAON-001
Vector information
Vectorliposome

Clinical Result

Cohort 1
Administration route intravenous injection
Dosage LErafAON, 2 weeks (total of 10 doses)
Pts 25
Age Adult, Older_Adult

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