Gene symbol | BCL2 | Synonyms | Bcl-2, PPP1R50 | Type of gene | protein-coding |
Chromosome | 18 | Map location | 18q21.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | BCL2 apoptosis regulator |
GTO ID | GTC1187 |
Trial ID | NCT00024440 |
Disease | Leukemia |
Altered gene | Bcl-2 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | Genasense|G3139|oblimersen sodium |
Co-treatment | filgrastim|cyclophosphamide|fludarabine phosphate |
Phase | Phase3 |
Recruitment status | Completed |
Title | Randomized Study Of Fludarabine And Cyclophosphamide With Or Without Genasense (Bcl-2 Antisense Oligonucleotide) In Subjects With Relapsed Or Refractory Chronic Lymphocytic Leukemia |
Year | 2001 |
Country | United States |
Company sponsor | Genta Incorporated |
Other ID(s) | CDR0000068932|GENTA-GL303|UCLA-0104008 |
Vector information | |||
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Cohort 1 | |||||
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