Basic Information

Gene symbol BCL2 Synonyms Bcl-2, PPP1R50 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description BCL2 apoptosis regulator

GTO ID GTC1187
Trial ID NCT00024440
Disease Leukemia
Altered gene Bcl-2
Therapeutic/Target gene Target gene
TherapyASO
Treatment Genasense|G3139|oblimersen sodium
Co-treatment filgrastim|cyclophosphamide|fludarabine phosphate
PhasePhase3
Recruitment statusCompleted
TitleRandomized Study Of Fludarabine And Cyclophosphamide With Or Without Genasense (Bcl-2 Antisense Oligonucleotide) In Subjects With Relapsed Or Refractory Chronic Lymphocytic Leukemia
Year2001
CountryUnited States
Company sponsorGenta Incorporated
Other ID(s)CDR0000068932|GENTA-GL303|UCLA-0104008
Vector information
VectorNo vector was used

Clinical Result

Cohort 1
Administration route intravenous infusion
Age Adult, Older_Adult

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