Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC1185
Trial ID NCT00021736
Disease Choroidal Neovascularization | Macular Degeneration
Altered gene VEGFA
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Macugen|pegaptanib|EYE001
PhasePhase2|Phase3
Recruitment statusCompleted
TitlePhase II/III Randomized, Double-Masked, Trial, to Establish the Safety and Efficacy of Intravitreal Injections of EYE001 (Anti-VEGF Pegylated Aptamer) Given Every 6 Weeks for 54 Weeks, in Patients With Exudative AMD).
Year2001
CountryUnited States
Company sponsorEyetech Pharmaceuticals
Other ID(s)EOP1004B

Clinical Result

Cohort 1
Administration route intravitreal injection
Age Adult, Older_Adult

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