Gene symbol | MGMT | Synonyms | None | Type of gene | protein-coding |
Chromosome | 10 | Map location | 10q26.3 | dbXrefs | |
Description | O-6-methylguanine-DNA methyltransferase |
GTO ID | GTC1155 |
Trial ID | NCT00003567 |
Disease | Solid Tumor |
Altered gene | MGMT |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | MGMT RTV PBSC |
Phase | Phase1 |
Recruitment status | Terminated |
Title | Mutant MGMT Gene Transfer Into Human Hematopoietic Progenitors to Protect Hematopoiesis During O6-Benzylguanine (BG, NSC 637037) and Carmustine Followed by Temozolomide Therapy of Advanced Solid Tumors |
Year | 1999 |
Country | United States |
Company sponsor | Case Comprehensive Cancer Center |
Other ID(s) | CWRU2Y97|R21CA076192|P30CA043703|CASE-CWRU-2Y97|NCI-T97-0060|CASE-2Y97 |
Vector information | |||
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Cohort 1 | |||||||
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