Gene symbol | RAF1 | Synonyms | CMD1NN, CRAF, NS5, Raf-1, c-Raf | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3p25.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | Raf-1 proto-oncogene, serine/threonine kinase |
GTO ID | GTC1152 |
Trial ID | NCT00003236 |
Disease | Breast Cancer |
Altered gene | C-Raf |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | ISIS 5132|CGP 69846A |
Phase | Phase2 |
Recruitment status | Completed |
Title | Randomized Phase II Study of Human C-raf Kinase Antisense Oligonucleotide Isis 5132 (CGP 69846A) or Human Pkc-Alpha Antisence Oligonucleotide ISIS 3521 (CGP 64128A) in Women With Previously Treated Matastatic Breast Cancer |
Year | 1999 |
Country | United States |
Company sponsor | Eastern Cooperative Oncology Group |
Other ID(s) | CDR0000066108|ECOG-3197 |
Vector information | |||
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Cohort 1 | |||||
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