Basic Information

Gene symbol RAF1 Synonyms CMD1NN, CRAF, NS5, Raf-1, c-Raf Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description Raf-1 proto-oncogene, serine/threonine kinase

GTO ID GTC1152
Trial ID NCT00003236
Disease Breast Cancer
Altered gene C-Raf
Therapeutic/Target gene Target gene
TherapyASO
Treatment ISIS 5132|CGP 69846A
PhasePhase2
Recruitment statusCompleted
TitleRandomized Phase II Study of Human C-raf Kinase Antisense Oligonucleotide Isis 5132 (CGP 69846A) or Human Pkc-Alpha Antisence Oligonucleotide ISIS 3521 (CGP 64128A) in Women With Previously Treated Matastatic Breast Cancer
Year1999
CountryUnited States
Company sponsorEastern Cooperative Oncology Group
Other ID(s)CDR0000066108|ECOG-3197
Vector information
VectorNo vector was used

Clinical Result

Cohort 1
Administration route intravenous infusion
Age Adult, Older_Adult

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