Gene symbol | MAGEA4 | Synonyms | CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B | Type of gene | protein-coding | |
Chromosome | X | Map location | Xq28 | dbXrefs | Entrez:4103 MIM:300175 HGNC:HGNC:6802 Ensembl:ENSG00000147381 AllianceGenome:HGNC:6802 | |
Description | MAGE family member A4 |
GTO ID | GTC1124 |
Trial ID | JPRN-UMIN000010729 |
Disease | Esophageal Cancer |
Altered gene | MAGE-A4 |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | MAGE-A4 TCR-T cells |
Phase | Phase1 |
Recruitment status | Not Recruiting |
Title | Adoptive transfer of lymphocytes transduced with MAGE-A4-specific TCR gene following lymphodepleting conditioning for therapy-resistant esophageal cancer |
Year | 2013 |
Country | Japan |
Company sponsor | Department of Immuno-gene Therapy, Mie University Graduate School of Medicine |
Cohort1: dose level 1 | |||||||||
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Cohort2: dose level 2 | |||||||||
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