Basic Information

Gene symbol MAGEA4 Synonyms CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B Type of gene protein-coding
Description MAGE family member A4

GTO ID GTC1124
Trial ID JPRN-UMIN000010729
Disease Esophageal Cancer
Altered gene MAGE-A4
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment MAGE-A4 TCR-T cells
PhasePhase1
Recruitment statusNot Recruiting
TitleAdoptive transfer of lymphocytes transduced with MAGE-A4-specific TCR gene following lymphodepleting conditioning for therapy-resistant esophageal cancer
Year2013
CountryJapan
Company sponsorDepartment of Immuno-gene Therapy, Mie University Graduate School of Medicine

Clinical Result

Cohort1: dose level 1
Administration route infusion
Dosage 1E9 cells
Donor type autologous
Age Adult, Older_Adult
Cohort2: dose level 2
Administration route infusion
Dosage 5E9 cells
Donor type autologous
Age Adult, Older_Adult

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