Gene symbol | EPHB4 | Synonyms | CMAVM2, HFASD, HTK, LMPHM7, MYK1, TYRO11 | Type of gene | protein-coding |
Chromosome | 7 | Map location | 7q22.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | EPH receptor B4 |
GTO ID | GTC1118 |
Trial ID | JPRN-jRCT2033230299 |
Disease | Ewing Sarcoma |
Altered gene | EPHB4 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | EPHB4 CAR-T cells |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Phase I study of non-viral gene-modified CAR-T cell therapy for ewing sarcoma or malignant solid tumors with expression of EPHB4 receptor |
Year | 2023 |
Country | Japan |
Company sponsor | National Cancer Center Hospital East |
Cohort 1 | |||||||||
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