Basic Information

Gene symbol ERBB2 Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description erb-b2 receptor tyrosine kinase 2

GTO ID GTC1117
Trial ID JPRN-jRCT2033220088
Disease Osteosarcoma
Altered gene HER2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment HER2 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitlePhase I clinical study on the safety of HER2-specific chimeric antigen receptor (CAR) gene-modified T cell therapy
Year2022
CountryJapan
Company sponsorShinshu University Hospital

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 8.3E5~2.7E6 cells/kg
Pts 12
Age Child, Adult, Older_Adult

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